Module 04 |
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Submodule 4A Biotransformation, S&B Chapter 3 (lightly) |
1. What are Phase I transformations. 2. What are Phase II transformation. 3. What are microsomes and how do you make them? 4. What is the P450 superfamily of enzymes? 5. What kinds of biotransformation are mediated by P450 enzymes? 8. Describe in general terms what Glucuronidation involves. 9. What is Glutathione? 10. Vocabulary words: biotransformation, bioactivation, hydrophilic, conjugated, First pass, enterohepatic recirculation, |
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Submodule 4B Scientific Literature and Ethics |
Understand the hierarchy of sources of information. What goes into a peer review. | |
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Submodule 4C Cancer I, the science, S&B Chapter 5 |
1. Vocabulary: Carcinogen, carcinoma, sarcoma,
initiation, transformed, neoplasm, malignant, metastasis, progression, genetic
carcinogens, epigenetic carcinogens, initiators, promoters, point mutation,
frame shift mutations, nonsense mutations, changes in chromosome structure,
missing or lost chromosomes, Oncogenes, Proto-oncogenes, growth factors,
tumor supressor genes, p53, 2. Describe the generalized process or stages for a carcinogen chemical to a metastatic tumor 3. Differentiate genetic and epigenetic carcinogen |
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Submodule 4D Paper |
Start thinking about the paper and topic. | |
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Submodule 4E UAF Library |
Learn about modern library electronic searching, databases, and resources. | |