Submodule 9A

Immunotoxicology

Vocabulary: diapedesis, CHEMOTAXIS, PHAGOCYTOSIS, OXIDATIVE BURST, Neutrophils, MAST CELLS, Immunoglobulin E antibody (IgE),antigens, antibodies, cytokines (aka lymphokines), T cells, B cells, TDI, Type I, II, III, and IV response.

Understand the basic steps in antibody production, Describe, including cell types, how an anaphylatic response comes about.

Submodule 9B

Hormonally Active Agents (aka Endocrine Disrupters)

Vocabulary: Estradiol-(17ß),Estrogens, xenoestrogens, Genotypic sex, Phenotypic (Genital) sex.

Human in utero sexual differentiation and how an steroid-type hormone could affect it.
Current state of the science of HAAs.

Submodule 9C

Mixtures

Understand the basic types of interactions: No interaction, Additive effects, Synergistic effects,Potentiation, Functional Antagonism, Chemical Antagonism, Dispositional Antagonism, Receptor Antagonism (Blockers)

Submodule 9D

Metals

Learn some general information about metal. Chelation. Learn the main effects of some "important" metals, such as Arsenic, Cadmium, Chromium, Lead, Mercury