Submodule 6A Reproductive Toxicology, S&B Chapter 6 |
1. Vocabulary: mitosis, meiosis, chromatin, autosomal chromosomes, alleles,
X and Y chromosomes, haploid, diploid, crossing over, testes, seminiferous
tubules, testosterone, LH, FSH, GnRF, spermatozoa, semen, blood- testis,
ovaries, fallopian tubes, uterus, endometrium, primary oocytes, primary
follicles, secondary follicles, secondary oocyte, polar body, zygote,
placenta, teratology, teratogen, Multi-generational reproduction test. 4. How might a child be exposed to phthalate esters? 5. The great range of chemicals and other insults to various stages of reproduction. 6. Sensitivity during organogensis 7. Breast milk as an exposure route for infants. |
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Submodule 6B Reproductive Examples |
1. Describe the thalidomide tragedy. What went wrong with the system? 2. DES. What happened. Multi-generational studies. |
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Submodule 6C Respiratory Toxicology, S&B Chapter 7 |
1. Vocabulary: conducting airways, cilia, mucus, bronchioles,
alveoli, surfactant, Clara cell, macrophage, parenchyma, stroma, elastic
recoil, pneumoconiosis, 3. Describe irritation to conducting airways, what happens. 7. Describe the change in velocity, airway diameter, and airway surface area, going from trachea to alveoli. |
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Submodule 6D Particulates |
Differentiate the causes of asbestosis vs. silicosis. | |
Submodule 6E Resources: IRIS, ATSDR, IARC |